An Integrated Microfluidic System for Cholangiocarcinoma Diagnosis from Bile by Using Specific Affinity Probes

Published in Sensors and Actuators B: Chemical, 2022

Abstract

This paper presents an integrated microfluidic system designed for the rapid diagnosis of cholangiocarcinoma (CCA) from bile samples using specific affinity probes. The device enables label-free and real-time detection of biomarkers associated with CCA, offering a promising tool for early disease detection and clinical management.

Key Contributions

  • Development of a miniaturized microfluidic platform for biomarker detection
  • Integration of affinity-based capture and detection mechanisms
  • Demonstration of clinical applicability using patient bile samples
  • Enhanced sensitivity and specificity compared to conventional diagnostic methods

Recommended citation: Tsung-Han Lu et al. (2022). "An Integrated Microfluidic System for Cholangiocarcinoma Diagnosis from Bile by Using Specific Affinity Probes." Sensors and Actuators B: Chemical.
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