An Integrated Microfluidic Platform for Cholangiocarcinoma Diagnosis from Clinical Bile by Utilizing Multiple Affinity Reagents
Published in National Tsing Hua University Electronic Theses and Dissertations System, 2021
Thesis Overview
This master’s thesis describes the design, fabrication, and validation of an integrated microfluidic platform for cholangiocarcinoma diagnosis. The platform leverages multiple affinity reagents to detect and analyze biomarkers in clinical bile samples, providing a rapid and accurate diagnostic tool.
Research Objectives
- Design of microfluidic device architecture for biomarker capture and detection
- Integration of multiple affinity probes for enhanced specificity
- Validation using clinical bile samples from CCA patients
- Development of automated detection and analysis protocols
Key Achievements
- Successfully demonstrated clinical applicability of the microfluidic platform
- Achieved high sensitivity and specificity for CCA biomarker detection
- Published findings in peer-reviewed journals
- Contributed to advancement of lab-on-a-chip technology for medical diagnostics
Recommended citation: Tsung-Han Lu. (2021). "An Integrated Microfluidic Platform for Cholangiocarcinoma Diagnosis from Clinical Bile by Utilizing Multiple Affinity Reagents." Master's thesis, National Tsing Hua University.
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